Journal: Bioactive Materials
Article Title: ROS-responsive & scavenging NO nanomedicine for vascular diseases treatment by inhibiting endoplasmic reticulum stress and improving NO bioavailability
doi: 10.1016/j.bioactmat.2024.03.010
Figure Lengend Snippet: Characterization of different NPs. (A) Schematic illustration of β-CD-PBA synthesis and t-PBA&NO fabrication. a, DMF, 100 °C, 8 h; b, CDI, DCM, 1 h; c, DMAP, DMF, 24 h. The 1 H NMR (B), UV–vis spectrum (C) and FT-IR (D) of β-CD-PBA, PBA, and β-CD. The intensity number (E) and zeta potential (F) of different nanoparticles. The hydrodynamic diameters (G) and TEM results (G, the inner image) of t-PBA&NO NP. Scale bar, 100 nm. (H) ROS-responsive 24-h release profiles of t-PBA&NO NP in PBS with or without H 2 O 2 . DPPH assay (I) and ABTS assay (J) of PBA&NO NP. Data are presented as mean ± SD (n = 3).
Article Snippet: Mitochondrial Membrane Potential Kit (JC-10 Assay) and ABTS Free Radical Scavenging Capacity Assay Kit were purchased from Solarbio Science & Technology Co., Ltd. (Beijing, China) .
Techniques: Zeta Potential Analyzer, DPPH Assay, ABTS Assay